C.V.
2013 Research Associate/Project Manager. Departments of Entomology and Biology, Penn State
2007 – 2012 Research Career Development Fellow. Malawi-Liverpool-Wellcome Trust Clinical Research Programme and Liverpool School of Tropical Medicine.
2001 – 2007 Research Associate. MLW Clinical Research Programme and University of Liverpool
1997 – 2001 PhD. The Walter and Eliza Hall Institute of Medical Research and The University of Melbourne
1993 – 1996 Bachelor of Science (Hons). Department of Genetics, The University of Melbourne
2013 Research Associate/Project Manager. Departments of Entomology and Biology, Penn State
2007 – 2012 Research Career Development Fellow. Malawi-Liverpool-Wellcome Trust Clinical Research Programme and Liverpool School of Tropical Medicine.
2001 – 2007 Research Associate. MLW Clinical Research Programme and University of Liverpool
1997 – 2001 PhD. The Walter and Eliza Hall Institute of Medical Research and The University of Melbourne
1993 – 1996 Bachelor of Science (Hons). Department of Genetics, The University of Melbourne
Research interests
Publications
Katangwe, T., Purcell, J., Bar-Zeev, N., Denis, B., Montgomery, J., Alaerts, M., Heyderman, R. S., Dance, D. A. B., Kennedy, N., Feasey, N. and Moxon, C. A. (2013) Human melioidosis, Malawi, 2011. Emerg. Infect. Dis. 19 (6) : 981-4
Tembo, D.L., Montgomery, J. And Wassmer, S. C. (2013) A simple protocol for platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes in a resource poor setting. J. Vis. Exp. 75 e4316, doi : 10.3791/4316
Milner, D. A., Vareta, J., Valim, C., Montgomery, J., Daniels, R. F., Volkman, S. K., Neafsey, D. E., Park, D. J., Schaffner, S. F., Mahesh, N. C., Barnes, K. G., Rosen, D. M., Lukens, A. K., Van-Tyne, D., Wiegand, R. C., Sabeti, P. C., Seydel, K. B., Glover, S. J., Kamiza, S., Molyneux, M. E., Taylor, T. E., Wirth, D. F. (2012) Human cerebral malaria and Plasmodium falciparum genotypes in Malawi. Malaria J. 11 : 35
Tembo, D. and Montgomery, J. (2010) var gene expression and human Plasmodium pathogenesis. Future Micro 5 : 805-815
Phiri, H., Montgomery, J., Molyneux, M., Craig, A. (2009) Competitive endothelial adhesion between Plasmodium falciparum isolates under physiological flow conditions. Malaria J. 8 : 214
Bell, D.J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D.A., Molyneux, M.E., Ward, S.A., Winstanley, P.A., Lalloo, D.G. (2009) Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. Malaria J. 8 (1) : 204
Milner, Jr., D.A., Montgomery, J., Seydel, K.B. And Rogerson, S.J. (2008) Severe malaria in children and pregnancy: an update and perspective. Trends Parasitol. 24 (12) : 590-5
Dembo, E.G., Mwapasa, V., Montgomery, J., Craig, A.G., Porter, K.A., Meshnick, S.R., Molyneux, M.E. and Rogerson, S.J. (2008) The impact of HIV infection in pregnant women on variant specific immunity to malaria. Clin. Vaccine Immunol. 15 : 617-621
Montgomery, J., Mphande, F.A., Berriman, M., Pain, A., Rogerson, S.J., Taylor, T.E., Molyneux, M.E., and Craig, A. (2007) Differential var gene expression in the organs of patients dying of falciparum malaria. Mol. Microbiol. 65 : 959-67
Bull, P.C., Kyes, S., Buckee, C.O., Montgomery, J.,Kortok, M.M., Newbold, C.I. and Marsh, K. (2007) An approach to classification of sequence tags sampled from Plasmodium falciparum var genes. Mol. Biochem. Parasitol. 154 : 98-102
Dembo, E., Phiri, H., Montgomery, J.,Molyneux, M.andRogerson, S. (2006) Are P. falciparum parasites present in peripheral blood genetically the same as those sequestered in the tissues? Am. J. Trop. Med. Hyg. 74 : 730-732
Montgomery, J., Milner Jr., D., Tse, M., Njobvu, A., Kayira, K., Dzamalala, C., Taylor, T., Rogerson, S., Craig, A. and Molyneux, M. (2006) Genetic analysis of circulating and sequestered populations of Plasmodium falciparum in fatal paediatric malaria. J. Infect. Dis. 194 : 115-122
Swarthout T.D., van den Broek I.V., Kayembe, G., Montgomery, J., Pota, H., Roper, C. (2006) Artesunate + amodiaquine and artesunate + sulfadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulfadoxine and pyrimethamine resistant haplotypes. Trop. Med. Int. Health 11 : 1503-11
Hamour, S., Melaku, Y., Keus, K., Wambugu, J., Atkin, S., Montgomery, J., Ford, N., Hook, C., Checchi, F. (2005) Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations. Trans. R. Soc. Trop. Med. Hyg. 99 : 458-554
van den Broek, I., Amsalu, R., Balasegaram, M., Hepple, P., Alemu, E., Hussein, E.B., Al-Faith, M., Montgomery, J. and Checchi, F. (2005) Efficacy of two Artemisinin-combination therapies for uncomplicated falciparum malaria in children under 5 years, Malakal, Upper Nile State, Sudan. Malar. J. 4 : 14
Kedzierski, L., Montgomery, J., Bullen, D., Curtis, J., Gardiner, E., Jimenez-Ruiz, A. and Handman, E. (2004) A leucine-rich repeat motif of Leishmania parasite surface antigen 2 binds to macrophages through the complement receptor 3. J. Immunol. 172 : 4902-4906
Montgomery, J., Curtis, J. and Handman, E. (2002) Genetic and structural heterogeneity of proteophosphoglycans in Leishmania. Mol. Biochem. Para. 121 : 75-85
Jensen, A. T., Curtis, J., Montgomery, J., Handman, E. and Theander, T. G. (2001) Molecular and immunological characterisation of the glucose regulated protein 78 of Leishmania donovani. Biochim. Biophys. Acta 1549 : 73-87
Mair, G., Shi, H., Li, H., Djikeng, A., Aviles, H. O., Bishop, J.R., Falcone, F.H., Gavrilescu, C., Montgomery, J.L., Santori, M.I., Stern, L.S., Wang, Z., Ullu, E. and Tschudi, C. (2000) A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA. RNA 6 : 163-169
Montgomery, J., Ilg, T., Thompson, J. K., Kobe, B. and Handman, E. (2000) Identification and predicted structure of a leucine-rich repeat motif shared by Leishmania major proteophosphoglycan and Parasite Surface Antigen 2. Mol Biochem. Para. 107 : 289-295
Ilg, T., Montgomery, J., Stierhof, Y.-D. and Handman, E. (1999) Molecular cloning and characterization of a novel repeat-containing Leishmania major gene, ppg1, that encodes a membrane-associated form of proteophosphoglycan with a putative glycosylphosphatidyl anchor. J. Biol. Chem. 274 : 31410-31420
Katangwe, T., Purcell, J., Bar-Zeev, N., Denis, B., Montgomery, J., Alaerts, M., Heyderman, R. S., Dance, D. A. B., Kennedy, N., Feasey, N. and Moxon, C. A. (2013) Human melioidosis, Malawi, 2011. Emerg. Infect. Dis. 19 (6) : 981-4
Tembo, D.L., Montgomery, J. And Wassmer, S. C. (2013) A simple protocol for platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes in a resource poor setting. J. Vis. Exp. 75 e4316, doi : 10.3791/4316
Milner, D. A., Vareta, J., Valim, C., Montgomery, J., Daniels, R. F., Volkman, S. K., Neafsey, D. E., Park, D. J., Schaffner, S. F., Mahesh, N. C., Barnes, K. G., Rosen, D. M., Lukens, A. K., Van-Tyne, D., Wiegand, R. C., Sabeti, P. C., Seydel, K. B., Glover, S. J., Kamiza, S., Molyneux, M. E., Taylor, T. E., Wirth, D. F. (2012) Human cerebral malaria and Plasmodium falciparum genotypes in Malawi. Malaria J. 11 : 35
Tembo, D. and Montgomery, J. (2010) var gene expression and human Plasmodium pathogenesis. Future Micro 5 : 805-815
Phiri, H., Montgomery, J., Molyneux, M., Craig, A. (2009) Competitive endothelial adhesion between Plasmodium falciparum isolates under physiological flow conditions. Malaria J. 8 : 214
Bell, D.J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D.A., Molyneux, M.E., Ward, S.A., Winstanley, P.A., Lalloo, D.G. (2009) Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. Malaria J. 8 (1) : 204
Milner, Jr., D.A., Montgomery, J., Seydel, K.B. And Rogerson, S.J. (2008) Severe malaria in children and pregnancy: an update and perspective. Trends Parasitol. 24 (12) : 590-5
Dembo, E.G., Mwapasa, V., Montgomery, J., Craig, A.G., Porter, K.A., Meshnick, S.R., Molyneux, M.E. and Rogerson, S.J. (2008) The impact of HIV infection in pregnant women on variant specific immunity to malaria. Clin. Vaccine Immunol. 15 : 617-621
Montgomery, J., Mphande, F.A., Berriman, M., Pain, A., Rogerson, S.J., Taylor, T.E., Molyneux, M.E., and Craig, A. (2007) Differential var gene expression in the organs of patients dying of falciparum malaria. Mol. Microbiol. 65 : 959-67
Bull, P.C., Kyes, S., Buckee, C.O., Montgomery, J.,Kortok, M.M., Newbold, C.I. and Marsh, K. (2007) An approach to classification of sequence tags sampled from Plasmodium falciparum var genes. Mol. Biochem. Parasitol. 154 : 98-102
Dembo, E., Phiri, H., Montgomery, J.,Molyneux, M.andRogerson, S. (2006) Are P. falciparum parasites present in peripheral blood genetically the same as those sequestered in the tissues? Am. J. Trop. Med. Hyg. 74 : 730-732
Montgomery, J., Milner Jr., D., Tse, M., Njobvu, A., Kayira, K., Dzamalala, C., Taylor, T., Rogerson, S., Craig, A. and Molyneux, M. (2006) Genetic analysis of circulating and sequestered populations of Plasmodium falciparum in fatal paediatric malaria. J. Infect. Dis. 194 : 115-122
Swarthout T.D., van den Broek I.V., Kayembe, G., Montgomery, J., Pota, H., Roper, C. (2006) Artesunate + amodiaquine and artesunate + sulfadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulfadoxine and pyrimethamine resistant haplotypes. Trop. Med. Int. Health 11 : 1503-11
Hamour, S., Melaku, Y., Keus, K., Wambugu, J., Atkin, S., Montgomery, J., Ford, N., Hook, C., Checchi, F. (2005) Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations. Trans. R. Soc. Trop. Med. Hyg. 99 : 458-554
van den Broek, I., Amsalu, R., Balasegaram, M., Hepple, P., Alemu, E., Hussein, E.B., Al-Faith, M., Montgomery, J. and Checchi, F. (2005) Efficacy of two Artemisinin-combination therapies for uncomplicated falciparum malaria in children under 5 years, Malakal, Upper Nile State, Sudan. Malar. J. 4 : 14
Kedzierski, L., Montgomery, J., Bullen, D., Curtis, J., Gardiner, E., Jimenez-Ruiz, A. and Handman, E. (2004) A leucine-rich repeat motif of Leishmania parasite surface antigen 2 binds to macrophages through the complement receptor 3. J. Immunol. 172 : 4902-4906
Montgomery, J., Curtis, J. and Handman, E. (2002) Genetic and structural heterogeneity of proteophosphoglycans in Leishmania. Mol. Biochem. Para. 121 : 75-85
Jensen, A. T., Curtis, J., Montgomery, J., Handman, E. and Theander, T. G. (2001) Molecular and immunological characterisation of the glucose regulated protein 78 of Leishmania donovani. Biochim. Biophys. Acta 1549 : 73-87
Mair, G., Shi, H., Li, H., Djikeng, A., Aviles, H. O., Bishop, J.R., Falcone, F.H., Gavrilescu, C., Montgomery, J.L., Santori, M.I., Stern, L.S., Wang, Z., Ullu, E. and Tschudi, C. (2000) A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA. RNA 6 : 163-169
Montgomery, J., Ilg, T., Thompson, J. K., Kobe, B. and Handman, E. (2000) Identification and predicted structure of a leucine-rich repeat motif shared by Leishmania major proteophosphoglycan and Parasite Surface Antigen 2. Mol Biochem. Para. 107 : 289-295
Ilg, T., Montgomery, J., Stierhof, Y.-D. and Handman, E. (1999) Molecular cloning and characterization of a novel repeat-containing Leishmania major gene, ppg1, that encodes a membrane-associated form of proteophosphoglycan with a putative glycosylphosphatidyl anchor. J. Biol. Chem. 274 : 31410-31420
Miscellaneous