Nicole Mideo


Website:
Email: nlm12@psu.edu

C.V.

Education


PhD: Biology, Queen’s University, Canada [2009]           


Honours BSc: Zoology & Math, University of Toronto, Canada [2004]


Positions & Work Experience


Research Fellow: Centre for Infectious Disease Dynamics,  The Pennsylvania State University, USA [currently]


Research Fellow: Centre for Immunity, Infection and Evolution,  University of Edinburgh, UK  [2009-2011]


Research interests

Why do some parasites lead to severe disease while others lead to less severe disease? I am interested in understanding the factors that regulate patterns of infection within and between hosts, and how these factors interact to shape disease evolution. 


Publications

17. Mideo, N., Reece, S.E., Smith, A. Metcalf, C.J.E. (2013) The Cinderella Syndrome: Why do malaria-infected cells burst at midnight? Trends in Parasitology, 29: 10-16. 


16. Mideo, N., Acosta-Serrano, A., Aebischer, T., Brown, M.J.F., Fenton, A., Friman, V.-P., Restif, O., Reece, S.E., Webster, J.P. & Brown, S.P. (2013) Life in cells, hosts, and vectors: parasite evolution across scales. Infection, Genetics, & Evolution, 13: 344-347.


15. Brown, S.P., Cornforth, D., & Mideo, N. (2012) Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control. Trends in Microbiology, 20: 336-342.


14. Metcalf, C.J.E., Long, G.H., Mideo N., Forester J.S., Bjørnstad O.N., Graham A.L. (2012) Revealing mechanisms underlying variation in malaria virulence: effective propagation and host control of uninfected red blood cell supply. Journal of the Royal Society Interface, doi:10.1098/rsif.2012.0340.


13. Pollitt L.C., Reece S.E., Mideo N., Nussey D.H., & Colegrave N. (2012) The problem of autocorrelation in parasitology. PLoS Pathogens, 8: e1002590.


12. Mideo N., & Reece S.E. (2012) Plasticity in parasite phenotypes: evolutionary and ecological implications for disease. Future Microbiology, 7: 17-24.


11. Mideo N., Savill N.J., Chadwick W., Schneider P., Read A.F., Day T., & Reece S.E. (2011) Causes of variation in malaria infection dynamics: insights from theory and data. American Naturalist, 178: 174-188.


10. Mideo N., Nelson W.A., Reece S.E., Bell A.S., Read A.F., & Day T. (2011) Bridging scales in the evolution of infectious disease life histories: Application. Evolution, 65: 3298-3310.


9. Day T., Alizon S., & Mideo N. (2011) Bridging scales in the evolution of infectious disease life histories: Theory. Evolution, 65: 3448-3461.


8. Pollitt L.C., Mideo N., Drew D.R., Schneider P., Colegrave N., & Reece S.E. (2011) Competition and the evolution of reproductive restraint in malaria parasites. American Naturalist, 177: 358-367.


7. Mideo N. (2009) Parasite adaptations to within-host competition. Trends in Parasitology 25: 261-268.


6. Alizon S., Hurford A., Mideo N., & van Baalen M. (2009) Virulence evolution and the trade-off hypothesis: history, current state of affairs and future. Journal of Evolutionary Biology 22: 245-259.


5. Mideo N., Read A.F., & Day T. (2008) Modelling malaria pathogenesis. Cellular Microbiology 10: 1947-1955.


4. Mideo N., Barclay V.C., Chan B.H.K., Savill N.J., Read A.F., & Day T. (2008) Understanding and predicting strain-specific patterns of pathogenesis in the rodent malaria, Plasmodium chabaudi. American Naturalist 172: E214-238.


3. Mideo N., Alizon S., & Day T. (2008) Linking within- and between-host dynamics in the evolutionary epidemiology of infectious diseases. Trends in Ecology and Evolution 23: 511-517.


2. Mideo N., & Day T. (2008) On the evolution of reproductive restraint in malaria. Proceedings of the Royal Society, B 275: 1217-1224.                                 Nature Research Highlight (Evolutionary biology).


 1. Day T., Mideo N., & Alizon S. (2008) Why is HIV not insect-borne? Evolutionary Applications 1: 17-27.     


Miscellaneous